•  De Marco M, Basile A, Cammarota AL, Iannone C, Falco A, Marzullo L, Rosati A, Caporali R, Turco MC, Del Papa N. Response to antifibrotic therapy and decrease of circulating BAG3 protein levels in systemic sclerosis patients with reduced forced vital capacity. Biomed Pharmacother. 2024 Apr 11;174:116578. doi: 10.1016/j.biopha.2024.116578. Epub ahead of print. PMID: 38608524.
• Damiani V, Lamolinara A, Cicalini I, Cufaro MC, Del Pizzo F, Di Marco F, Del Boccio P, Dufrusine B, Hahne M, Lattanzio R, Pieragostino D, Iezzi M, Federici M, Turco MC, Maiorana A, Dionisi-Vici C, De Laurenzi V. Pancreatic beta-cell specific BAG3 knockout results in chronic hyperinsulinemia inducing insulin resistance. Mol Metab. 2023 Aug;74:101752. doi: 10.1016/j.molmet.2023.101752. Epub 2023 Jun 10. PMID: 37308077; PMCID: PMC10333681.
• Turco MC. BAG3 in the Heart. JACC Basic Transl Sci. 2023 Jul 24;8(7):840-842. doi: 10.1016/j.jacbts.2023.02.012. PMID: 37547063; PMCID: PMC10401284.
• Rosati A, Marzullo L, De Marco M, De Laurenzi V, D’Amico MF, Turco MC. Toxicity in combined therapies for tumours treatments: a lesson from BAG3 in the TME? Front Immunol. 2023 Jul 20;14:1241543. doi: 10.3389/fimmu.2023.1241543. PMID: 37554328; PMCID: PMC10406442.
• Basile A, Zannella C, De Marco M, Sanna G, Franci G, Galdiero M, Manzin A, De Laurenzi V, Chetta M, Rosati A, Turco MC, Marzullo L. Spike-mediated viral membrane fusion is inhibited by a specific anti-IFITM2 monoclonal antibody. Antiviral Res. 2023 Mar;211:105546. doi: 10.1016/j.antiviral.2023.105546. Epub 2023 Jan 18. PMID: 36669656.
• De Marco M, Gauttier V, Pengam S, Mary C, Ranieri B, Basile A, Festa M, Falco A, Reppucci F, Cammarota AL, Acernese F, De Laurenzi V, Sala G, Brongo S, Miyasaka M, Shalapour S, Vanhove B, Poirier N, Iaccarino R, Karin M, Turco MC, Rosati A, Marzullo L. Concerted BAG3 and SIRPα blockade impairs pancreatic tumor growth. Cell Death Discov. 2022 Mar 3;8(1):94. doi: 10.1038/s41420-022-00817-9. PMID: 35241649; PMCID: PMC889449.
• Rosati A, Turco MC. The co-chaperone BAG3: Orchestrator of the cellular task force in response to stress. J Cell Biochem. 2022 Jan;123(1):3. doi: 10.1002/jcb.30212. PMID: 35084061.
• Dufrusine B, Damiani V, Capone E, Pieragostino D, Dainese E, De Marco M, Reppucci F, Turco MC, Rosati A, Marzullo L, Sala G, Sallese M, De Laurenzi V. BAG3 induces fibroblasts to release key cytokines involved in pancreatic cell migration. J Cell Biochem. 2022 Jan;123(1):65-76. doi: 10.1002/jcb.30172. Epub 2021 Nov 6. PMID: 34741485; PMCID: PMC9297949.
• De Marco M, Del Papa N, Reppucci F, Iorio V, Basile A, Falco A, Iaccarino R, Brongo S, De Caro F, Capunzo M, Turco MC, Rosati A, Marzullo L. BAG3 induces α-SMA expression in human fibroblasts and its over-expression correlates with poorer survival in fibrotic cancer patients. J Cell Biochem. 2022 Jan;123(1):91-101. doi: 10.1002/jcb.30171. Epub 2021 Nov 6. PMID: 34741483; PMCID: PMC9297854.
• De Marco M, Falco A, Iaccarino R, Raffone A, Mollo A, Guida M, Rosati A, Chetta M, Genovese G, De Caro F, Capunzo M, Turco MC, Uversky VN, Marzullo L. An emerging role for BAG3 in gynaecological malignancies. Br J Cancer. 2021 Sep;125(6):789-797. doi: 10.1038/s41416-021-01446-2. Epub 2021 Jun 7. PMID: 34099896; PMCID: PMC8437940.
• De Marco M, Turco MC, Marzullo L. BAG3 in Tumor Resistance to Therapy. Trends Cancer. 2020 Dec;6(12):985-988. doi: 10.1016/j.trecan.2020.07.001. Epub 2020 Jul 25. PMID: 32718905.
• Marzullo L, Turco MC, De Marco M. The multiple activities of BAG3 protein: Mechanisms. Biochim Biophys Acta Gen Subj. 2020 Aug;1864(8):129628. doi: 10.1016/j.bbagen.2020.129628. Epub 2020 Apr 28. PMID: 32360144.
• Basile A, De Marco M, Festa M, Falco A, Iorio V, Guerriero L, Eletto D, Rea D, Arra C, Lamolinara A, Ballerini P, Damiani V, Rosati A, Sala G, Turco MC, Marzullo L, De Laurenzi V. Development of an anti-BAG3 humanized antibody for treatment of pancreatic cancer. Mol Oncol. 2019 Jun;13(6):1388-1399. doi: 10.1002/1878-0261.12492. Epub 2019 May 17. PMID: 30973679; PMCID: PMC6547619.
• Iorio V, De Marco M, Basile A, Eletto D, Capunzo M, Remondelli P, Sala G, Marzullo L, Rosati A, De Laurenzi V, Turco MC. CAF-Derived IL6 and GM-CSF Cooperate to Induce M2-like TAMs-Letter. Clin Cancer Res. 2019 Jan 15;25(2):892-893. doi: 10.1158/1078-0432.CCR-18-2455. PMID: 30647085.
• Terracciano S , Lauro G , Russo A , Vaccaro MC , Vassallo A , De Marco M , Ranieri B , Rosati A , Turco MC , Riccio R , Bifulco G , Bruno I . Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics. Chem Commun (Camb). 2018 Jul 5;54(55):7613-7616. doi: 10.1039/c8cc03399d. PMID: 29926854.
• De Marco M, Basile A, Iorio V, Festa M, Falco A, Ranieri B, Pascale M, Sala G, Remondelli P, Capunzo M, Firpo MA, Pezzilli R, Marzullo L, Cavallo P, De Laurenzi V, Turco MC, Rosati A. Role of BAG3 in cancer progression: A therapeutic opportunity. Semin Cell Dev Biol. 2018 Jun;78:85-92. doi: 10.1016/j.semcdb.2017.08.049. Epub 2017 Aug 31. PMID: 28864347.
• Iorio V, Rosati A, D’Auria R, De Marco M, Marzullo L, Basile A, Festa M, Pascale M, Remondelli P, Capunzo M, Sala G, Damiani V, Amodio G, Di Nicola M, Lattanzio R, Turco MC, De Laurenzi V. Combined effect of anti-BAG3 and anti-PD-1 treatment on macrophage infiltrate, CD8⁺ T cell number and tumour growth in pancreatic cancer. Gut. 2018 Apr;67(4):780-782. doi: 10.1136/gutjnl-2017-314225. Epub 2017 Aug 11. PMID: 28801350; PMCID: PMC5868239.
• Derosa G, Maffioli P, Rosati A, M M, Basile A, D’Angelo A, Romano D, Sahebkar A, Falco A, Turco MC. Evaluation of BAG3 levels in healthy subjects, hypertensive patients, and hypertensive diabetic patients. J Cell Physiol. 2018 Mar;233(3):1791-1795. doi: 10.1002/jcp.26093. Epub 2017 Aug 25. PMID: 28696030.
• Galdiero F, Bello AM, Spina A, Capiluongo A, Liuu S, De Marco M, Rosati A, Capunzo M, Napolitano M, Vuttariello E, Monaco M, Califano D, Turco MC, Chiappetta G, Vinh J, Chiappetta G. Identification of BAG3 target proteins in anaplastic thyroid cancer cells by proteomic analysis. Oncotarget. 2018 Jan 3;9(8):8016-8026. doi: 10.18632/oncotarget.23858. PMID: 29487711; PMCID: PMC5814278.
  
• Guerriero L, Palmieri G, De Marco M, Cossu A, Remondelli P, Capunzo M, Turco MC, Rosati A. The anti-apoptotic BAG3 protein is involved in BRAF inhibitor resistance in melanoma cells. Oncotarget. 2017 Jun 30;8(46):80393-80404. doi: 10.18632/oncotarget.18902. PMID: 29113311; PMCID: PMC5655206.
• Esposito V, Baldi C, Zeppa P, Festa M, Guerriero L, d’Avenia M, Chetta M, Zullo F, De Laurenzi V, Turco MC, Rosati A, Guida M. BAG3 Protein Is Over-Expressed in Endometrioid Endometrial Adenocarcinomas. J Cell Physiol. 2017 Feb;232(2):309-311. doi: 10.1002/jcp.25489. Epub 2016 Jul 22. PMID: 27414463.
• Carrizzo A, Damato A, Ambrosio M, Falco A, Rosati A, Capunzo M, Madonna M, Turco MC, Januzzi JL, De Laurenzi V, Vecchione C. The prosurvival protein BAG3: a new participant in vascular homeostasis. Cell Death Dis. 2016 Oct 20;7(10):e2431. doi: 10.1038/cddis.2016.321. PMID: 27763645; PMCID: PMC5133988.
• Rosati A, Basile A, D’Auria R, d’Avenia M, De Marco M, Falco A, Festa M, Guerriero L, Iorio V, Parente R, Pascale M, Marzullo L, Franco R, Arra C, Barbieri A, Rea D, Menichini G, Hahne M, Bijlsma M, Barcaroli D, Sala G, di Mola FF, di Sebastiano P, Todoric J, Antonucci L, Corvest V, Jawhari A, Firpo MA, Tuveson DA, Capunzo M, Karin M, De Laurenzi V, Turco MC. BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages. Nat Commun. 2015 Nov 2;6:8695. doi: 10.1038/ncomms9695. PMID: 26522614; PMCID: PMC4659838.
• d’Avenia M, Citro R, De Marco M, Veronese A, Rosati A, Visone R, Leptidis S, Philippen L, Vitale G, Cavallo A, Silverio A, Prota C, Gravina P, De Cola A, Carletti E, Coppola G, Gallo S, Provenza G, Bossone E, Piscione F, Hahne M, De Windt LJ, Turco MC, De Laurenzi V. A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy. Cell Death Dis. 2015 Oct 29;6(10):e1948. doi: 10.1038/cddis.2015.280. PMID: 26512958; PMCID: PMC4632305.
• Gandhi PU, Gaggin HK, Belcher AM, Harisiades JE, Basile A, Falco A, Rosati A, Piscione F, Januzzi JL Jr, Turco MC. Analysis of BAG3 plasma concentrations in patients with acutely decompensated heart failure. Clin Chim Acta. 2015 May 20;445:73-8. doi: 10.1016/j.cca.2015.02.048. Epub 2015 Mar 6. PMID: 25753466.
• Merabova N, Sariyer IK, Saribas AS, Knezevic T, Gordon J, Turco MC, Rosati A, Weaver M, Landry J, Khalili K. WW domain of BAG3 is required for the induction of autophagy in glioma cells. J Cell Physiol. 2015 Apr;230(4):831-41. doi: 10.1002/jcp.24811. PMID: 25204229; PMCID: PMC4373658.
• Iorio V, Festa M, Rosati A, Hahne M, Tiberti C, Capunzo M, De Laurenzi V, Turco MC. BAG3 regulates formation of the SNARE complex and insulin secretion. Cell Death Dis. 2015 Mar 12;6(3):e1684. doi: 10.1038/cddis.2015.53. PMID: 25766323; PMCID: PMC4385931.
• De Marco M, D’Auria R, Rosati A, Vitulano G, Gigantino A, Citro R, Piscione F, Zilinski J, Januzzi JL Jr, Turco MC. BAG3 protein in advanced-stage heart failure. JACC Heart Fail. 2014 Dec;2(6):673-5. doi: 10.1016/j.jchf.2014.05.012. Epub 2014 Sep 24. PMID: 25262365.
• Chiappetta G, Basile A, Barbieri A, Falco A, Rosati A, Festa M, Pasquinelli R, Califano D, Palma G, Costanzo R, Barcaroli D, Capunzo M, Franco R, Rocco G, Pascale M, Turco MC, De Laurenzi V, Arra C. The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth. Oncotarget. 2014 Aug 30;5(16):6846-53. doi: 10.18632/oncotarget.2261. PMID: 25149536; PMCID: PMC4196167.
• Citro R, d’Avenia M, De Marco M, Giudice R, Mirra M, Ravera A, Silverio A, Farina R, Silvestri F, Gravina P, Villa F, Puca AA, De Windt L, De Laurenzi V, Bossone E, Turco MC, Piscione F. Polymorphisms of the antiapoptotic protein bag3 may play a role in the pathogenesis of tako-tsubo cardiomyopathy. Int J Cardiol. 2013 Sep 30;168(2):1663-5. doi: 10.1016/j.ijcard.2013.03.050. Epub 2013 Apr 11. PMID: 23582692.
• De Marco M, Falco A, Basile A, Rosati A, Festa M, d’Avenia M, Pascale M, Dal Piaz F, Bisogni R, Barcaroli D, Coppola G, Piscione F, Gigantino A, Citro R, De Rosa R, Vitulano G, Virtuoso N, Manganelli F, Palermo E, Siano F, Rosato G, Hahne M, Tiberti C, De Laurenzi V, Turco MC. Detection of soluble BAG3 and anti-BAG3 antibodies in patients with chronic heart failure. Cell Death Dis. 2013 Feb 14;4(2):e495. doi: 10.1038/cddis.2013.8. PMID: 23412388; PMCID: PMC3734839.
• Rosati A, Basile A, Falco A, d’Avenia M, Festa M, Graziano V, De Laurenzi V, Arra C, Pascale M, Turco MC. Role of BAG3 protein in leukemia cell survival and response to therapy. Biochim Biophys Acta. 2012 Dec;1826(2):365-9. doi: 10.1016/j.bbcan.2012.06.001. Epub 2012 Jun 15. PMID: 22710027.
• Falco A, Festa M, Basile A, Rosati A, Pascale M, Florenzano F, Nori SL, Nicolin V, Di Benedetto M, Vecchione ML, Arra C, Barbieri A, De Laurenzi V, Turco MC. BAG3 controls angiogenesis through regulation of ERK phosphorylation. Oncogene. 2012 Dec 13;31(50):5153-61. doi: 10.1038/onc.2012.17. Epub 2012 Feb 6. PMID: 22310281.
• Rosati A, Bersani S, Tavano F, Dalla Pozza E, De Marco M, Palmieri M, De Laurenzi V, Franco R, Scognamiglio G, Palaia R, Fontana A, di Sebastiano P, Donadelli M, Dando I, Medema JP, Dijk F, Welling L, di Mola FF, Pezzilli R, Turco MC, Scarpa A. Expression of the antiapoptotic protein BAG3 is a feature of pancreatic adenocarcinoma and its overexpression is associated with poorer survival. Am J Pathol. 2012 Nov;181(5):1524-9. doi: 10.1016/j.ajpath.2012.07.016. Epub 2012 Aug 31. PMID: 22944597.
• Sariyer IK, Merabova N, Patel PK, Knezevic T, Rosati A, Turco MC, Khalili K. Bag3-induced autophagy is associated with degradation of JCV oncoprotein, T-Ag. PLoS One. 2012;7(9):e45000. doi: 10.1371/journal.pone.0045000. Epub 2012 Sep 12. PMID: 22984599; PMCID: PMC3440322.
• Franco R, Scognamiglio G, Salerno V, Sebastiani A, Cennamo G, Ascierto PA, Botti G, Turco MC, Rosati A. Expression of the anti-apoptotic protein BAG3 in human melanomas. J Invest Dermatol. 2012 Jan;132(1):252-4. doi: 10.1038/jid.2011.257. Epub 2011 Aug 18. PMID: 21850027.
• Chiappetta G, Basile A, Arra C, Califano D, Pasquinelli R, Barbieri A, De Simone V, Rea D, Giudice A, Pezzullo L, De Laurenzi V, Botti G, Losito S, Conforti D, Turco MC. BAG3 down-modulation reduces anaplastic thyroid tumor growth by enhancing proteasome-mediated degradation of BRAF protein. J Clin Endocrinol Metab. 2012 Jan;97(1):E115-20. doi: 10.1210/jc.2011-0484. Epub 2011 Nov 9. PMID: 22072743.