The term fibrosis describes the development of fibrous connective tissue, which physiologically occurs as a reparative response to injury or damage.
Fibrosis is due to COLLAGEN and other elements of the extracellular matrix produced by activated fibroblasts.
In fibrotic diseases, deregulated fibrosis causes excessive accumulation of fibrotic tissue, that impacts on organs' functions and can alter cellular physiology.
FIBROSYS is a Research-Based Company that carries on preclinical studies aimed at developing new diagnostic and therapeutic tools to counteract the fibrotic process that characterize the progression of many pathologies.
The FIBROSYS Team identified an extracellular form of the BAG3 protein, secreted by cancer cells and other cell types, that can be a useful diagnostic marker to monitor the disease progression.